NOVEL MEDICATED ANIMAL
FEED
Comparison
with Other
Products and
their Preparation
| Characteristics | Novel product and technology | Medication during feed formulation | Medication by coating the feed |
| Distribution of drug |
within
the bulk of the feed |
within the bulk of the feed | on the surface of the feed |
| Palatability
|
excellent-good |
excellent-good |
feed tastes like drug |
| Product safety |
good |
good |
tendency
for leaching |
| Drug delivery dose |
uniform | uniform | differences between pellets |
| Bioavailability |
very good | good-very good | no data |
| Medication efficiency |
very good | good-very
good |
uncertain |
| Product stability | stable |
stable (possible drug decompostion during extrusion) |
tendency for abrasion |
| Production starts from | formulated feed and drug | feed ingredients and drug | formulated feed and drug |
| Equipment used | a designated closed
equipment |
entire feed production
line |
a designated equipment |
| Equipment cleaning |
only designated equipment |
entire
production line |
only designated equipment |
| Production safety |
safe | as safe as the feed production is | hazardous in open mixers |